PRAKASH, Alka, LAIRD, Susan, LI, Tin C and LEDGER, William L (2006). Preliminary prospective study of the endocrinology of conception cycles and early pregnancy in women with antiphospholipid syndrome treated with low molecular weight heparin. Fertility and sterility, 85 (1), 165-170.
Full text not available from this repository.Abstract
OBJECTIVE : To examine whether there were any differences in the endocrinological profiles during conception cycle and early pregnancy between a control group and women with a history of recurrent miscarriage that was caused by antiphospholipid syndrome and that was treated with aspirin and low molecular weight heparin.
DESIGN : Prospective observational study.
SETTING : Recurrent Miscarriage Clinic, Department of Obstetrics and Gynaecology in a tertiary care centre.
PATIENT(S) : Five women with recurrent pregnancy loss were recruited as cases, whereas another five women having natural cycle donor insemination were used as control.
INTERVENTION(S) : Serial measurement of serum beta-hCG, activin A, and inhibin A was performed from postovulatory day 12 until 11 weeks of gestation.
MAIN OUTCOME MEASURE(S) : Comparison of levels of beta-hCG, activin A, and inhibin A at the time of conception onwards till 11 weeks in the two groups.
RESULT(S) : There were no significant differences between the two groups.
CONCLUSION(S) : There does not appear to be any obvious endocrinological alteration in the conception cycle of women with antiphospholipid syndrome compared with a control group. Furthermore, the initiation of heparin does not produce a significant change in activin A and inhibin A levels.
Item Type: | Article |
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Research Institute, Centre or Group - Does NOT include content added after October 2018: | Biomedical Research Centre |
Identification Number: | https://doi.org/10.1016/j.fertnstert.2005.07.1288 |
Page Range: | 165-170 |
Depositing User: | Jamie Young |
Date Deposited: | 28 May 2015 10:52 |
Last Modified: | 18 Mar 2021 18:46 |
URI: | https://shura.shu.ac.uk/id/eprint/9907 |
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