NEWTON, K. A., CLENCH, M. R., DESHMUKH, R., JEYASEELAN, K. and STRONG, P. N. (2007). Mass fingerprinting of toxic fractions from the venom of the Indian red scorpion, mesobuthus tamulus: biotope-specific variation in the expression of venom peptides. Rapid communications in mass spectrometry, 21 (21), 3467-3476.
Full text not available from this repository.Abstract
The red scorpion, Mesobuthus tamulus, is found in two distinct biotopes within the Indian state of Maharastra - a tropical, sea-level biotope and a semi-arid biotope, up to 600 m. Scorpions from these two geographical areas show marked differences in toxicity. Using mass spectrometry, we have shown biotope-specific variation in the expression of peptides from scorpions collected from these two distinct areas. Matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOFMS) and reversed-phase liquid chromatography/electrospray ionisation mass spectrometry (LC/ESI-MS) were assessed as techniques for obtaining mass fingerprint data. On line LC/ESI-MS was judged to be the method of choice and unique biotope-specific mass fingerprints, with key diagnostic markers, were obtained.
Item Type: | Article |
---|---|
Research Institute, Centre or Group - Does NOT include content added after October 2018: | Biomedical Research Centre |
Identification Number: | https://doi.org/10.1002/rcm.3240 |
Page Range: | 3467-3476 |
Depositing User: | Ann Betterton |
Date Deposited: | 12 Mar 2008 |
Last Modified: | 18 Mar 2021 21:45 |
URI: | https://shura.shu.ac.uk/id/eprint/392 |
Actions (login required)
View Item |
Downloads
Downloads per month over past year