Sex-based differences in severity and mortality in COVID-19.

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ALWANI, Mustafa, YASSIN, Aksam, AL-ZOUBI, Raed M., ABOUMARZOUK, Omar M., NETTLESHIP, Joanne, KELLY, Daniel, AL-QUDIMAT, Ahmad R. and SHABSIGH, Ridwan (2021). Sex-based differences in severity and mortality in COVID-19. Rev Med Virol, 31 (6). [Article]

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28405:570779

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Abstract

The current coronavirus disease (COVID-19) pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a male bias in severity and mortality. This is consistent with previous coronavirus pandemics such as SARS-CoV and MERS-CoV, and viral infections in general. Here, we discuss the sex-disaggregated epidemiological data for COVID-19 and highlight underlying differences that may explain the sexual dimorphism to help inform risk stratification strategies and therapeutic options.

More Information

Official URL:

https://onlinelibrary.wiley.com/doi/10.1002/rmv.22...

Open Access URL:

https://onlinelibrary.wiley.com/doi/epdf/10.1002/r...

Open Access Version:

Published version

Uncontrolled Keywords:

COVID-19; dimorphism; sex; 1108 Medical Microbiology; Virology

Event Location:

England

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