MADEN-WILKINSON, Tom, DEGENS, H, JONES, DA and MCPHEE, JS (2013). Comparison of MRI and DXA to measure muscle size and age-related atrophy in thigh muscles. Journal of Musculoskeletal and Neuronal Interactions, 13 (3), 320-328.
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Abstract
Objectives: Magnetic resonance imaging (MRI) and dual-energy x-ray absorptiometry (DXA) were used to examine the thigh lean mass in young and old men and women. Methods: A whole-body DXA scan was used to estimate thigh lean mass in young (20 men; 22.4±3.1y; 18 women; 22.1±2.0y) and older adults (25 men; 72.3±4.9y; 28 women; 72.0±4.5y). Thigh lean mass deter-mined with a thigh scan on the DXA or full thigh MRI scans were compared. Results: Although the thigh lean mass quantified by DXA and MRI in young and older participants were correlated (R2=0.88; p<0.001) the magnitude of the differences in thigh lean mass between young and old was smaller with DXA than MRI (old vs. young men 79.5±13.1% and 73.4±11.2%; old vs. young women 88.6±11.8% and 79.4±12.3%, respectively). Detailed analysis of MRI revealed 30% smaller quadriceps muscles in the older than young individuals, while the other thigh muscles were only 18% smaller. Conclusions: DXA underestimates the age-related loss of thigh muscle mass in comparison to MRI. The quadriceps muscles were more susceptible to age-related atrophy compared with other thigh muscles.
Item Type: | Article |
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Uncontrolled Keywords: | 1103 Clinical Sciences; 1109 Neurosciences; 1116 Medical Physiology; Endocrinology & Metabolism |
Page Range: | 320-328 |
SWORD Depositor: | Symplectic Elements |
Depositing User: | Symplectic Elements |
Date Deposited: | 08 Jun 2021 15:07 |
Last Modified: | 08 Jun 2021 15:15 |
URI: | https://shura.shu.ac.uk/id/eprint/27972 |
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