Cognitive behavioural therapy for insomnia does not appear to have a substantial impact on early markers of cardiovascular disease: A preliminary randomized controlled trial

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JOHANN, Anna Friederike, HERTENSTEIN, Elisabeth, FEIGE, Bernd, AKRAM, Umair, HOLUB, Florian, BAGLIONI, Chiara, DOMSCHKE, Katharina, SCHRAMM, Elisabeth, NISSEN, Christoph, KYLE, Simon D, RIEMANN, Dieter, BIERMANN, Jürgen and SPIEGELHALDER, Kai (2020). Cognitive behavioural therapy for insomnia does not appear to have a substantial impact on early markers of cardiovascular disease: A preliminary randomized controlled trial. Journal of Sleep Research. [Article]

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Abstract
According to the World Health Organization, cardiovascular diseases are the leading cause of death in the world. Therefore, early prevention of these diseases is a public health priority. Epidemiological data suggest that insomnia may be a modifiable risk factor for cardiovascular diseases. A randomized controlled trial in a sample of insomnia patients without cardiovascular disease was conducted to investigate the effects of insomnia treatment on early markers of cardiovascular diseases assessed by 24‐hr ambulatory blood pressure, heart rate and heart rate variability monitoring, and morning fasting blood samples. Forty‐six patients with insomnia disorder were randomized to cognitive behavioural therapy for insomnia (CBT‐I; n = 23) or a waitlist control condition (n = 23). Contrary to the hypothesis, intention‐to‐treat analyses did not show any significant treatment effects on early markers of cardiovascular disease (d = 0.0–0.6) despite successful insomnia treatment (d = 1.3). Potential methodological and conceptual reasons for these negative findings are discussed. Future studies might include larger sample sizes that are at risk of cardiovascular diseases and focus on other cardiovascular markers.
More Information
Open Access URL:
https://onlinelibrary.wiley.com/doi/full/10.1111/j...
Open Access Version:
Published version
Uncontrolled Keywords:
11 Medical and Health Sciences; 17 Psychology and Cognitive Sciences; Neurology & Neurosurgery

Identifiers

Identification Number:
10.1111/jsr.13102
ORCID for Anna Friederike Johann: ORCID iD orcid.org/0000-0001-7816-6658
ORCID for Bernd Feige: ORCID iD orcid.org/0000-0002-9436-1258
ORCID for Umair Akram: ORCID iD orcid.org/0000-0003-0150-9274
ORCID for Chiara Baglioni: ORCID iD orcid.org/0000-0003-3150-7755
ORCID for Christoph Nissen: ORCID iD orcid.org/0000-0001-9809-0275
ORCID for Dieter Riemann: ORCID iD orcid.org/0000-0002-1968-6220

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Item Type:
Article
SWORD Depositor:
Symplectic Elements
Depositing User:
Symplectic Elements
Date Deposited:
01 Jul 2020 15:51
Last Modified:
18 Dec 2024 21:34
Date of first compliant deposit:
30 June 2020
Date of first compliant Open Access:
1 July 2020
Version of first compliant deposit:
Version of Record
URI:
https://shura.shu.ac.uk/id/eprint/26547
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