Changes in insulin sensitivity in response to different modalities of exercise: A review of the evidence

MANN, S., BEEDIE, C., BALDUCCI, S., ZANUSO, S., ALLGROVE, J., BERTIATO, F. and JIMENEZ GUTIERREZ, Alfonso (2014). Changes in insulin sensitivity in response to different modalities of exercise: A review of the evidence. Diabetes/Metabolism Research and Reviews, 30 (4), 257-268.

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Open Access URL: https://doi.org/10.1002/dmrr.2488 (Published version)
Link to published version:: https://doi.org/10.1002/dmrr.2488

Abstract

Summary: Type 2 diabetes is an increasingly prevalent condition with complications including blindness and kidney failure. Evidence suggests that type 2 diabetes is associated with a sedentary lifestyle, with physical activity demonstrated to increase glucose uptake and improve glycaemic control. Proposed mechanisms for these effects include the maintenance and improvement of insulin sensitivity via increased glucose transporter type four production. The optimal mode, frequency, intensity and duration of exercise for the improvement of insulin sensitivity are however yet to be identified. We review the evidence from 34 published studies addressing the effects on glycaemic control and insulin sensitivity of aerobic exercise, resistance training and both combined. Effect sizes and confidence intervals are reported for each intervention and meta-analysis presented. The quality of the evidence is tentatively graded, and recommendations for best practice proposed. © 2013 The Authors. Diabetes/Metabolism Research and Reviews published by John Wiley & Sons, Ltd.

Item Type: Article
Uncontrolled Keywords: insulin sensitivity; aerobic exercise; resistance training; combined modalities; aerobic exercise; combined modalities; insulin sensitivity; resistance training; Diabetes Mellitus, Type 2; Evidence-Based Medicine; Exercise; Health Policy; Health Promotion; Humans; Insulin Resistance; Muscle, Skeletal; Resistance Training; Muscle, Skeletal; Humans; Diabetes Mellitus, Type 2; Insulin Resistance; Exercise; Evidence-Based Medicine; Health Policy; Health Promotion; Resistance Training; 1103 Clinical Sciences; Endocrinology & Metabolism
Identification Number: https://doi.org/10.1002/dmrr.2488
Page Range: 257-268
SWORD Depositor: Symplectic Elements
Depositing User: Symplectic Elements
Date Deposited: 13 Apr 2021 14:42
Last Modified: 13 Apr 2021 14:45
URI: https://shura.shu.ac.uk/id/eprint/26517

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