A rationally designed cocatalyst for the Morita–Baylis–Hillman reaction

Tools

JONES, Charlotte E.S., TUREGA, Simon M., CLARKE, Matthew L. and PHILP, Douglas (2008). A rationally designed cocatalyst for the Morita–Baylis–Hillman reaction. Tetrahedron Letters, 49 (31), 4666-4669. [Article]

Abstract
More Information
Metrics
Share

[+][-]

Abstract

The application of electronic structure calculations to a key transition state in the reaction manifold of the Morita–Baylis–Hillman reaction allows the design of two bis(thiourea) cocatalysts capable of accelerating this reaction through the hydrogen bond mediated recognition of both the nucleophile and the electrophile.

More Information

Official URL:

http://dx.doi.org/10.1016/j.tetlet.2008.05.037

Additional Information:

Available online 11 May 2008

Research Institute, Centre or Group - Does NOT include content added after October 2018:

Biomedical Research Centre

Page Range:

4666-4669

Identifiers

Identification Number:

10.1016/j.tetlet.2008.05.037