Efficiency oriented, hybrid approach for modelling deformable particles in three dimensions

In this paper, we demonstrate a new, rigorous, accurate and efficient model for simulating the flow of a suspension of deformable particles. The model uses a hybrid system: an Eulerian approach is used for the Navier-Stokes solver and a Lagrangian approach for the evolution of the DPs mesh. We demonstrate in this manuscript the capabilities of the model by simulating more than 130 deformable RBC in a tube of 60 x 30 x 30 mu m the transverse migration of 20 vesicles at a low concentration (25% by volume) in a capillary tube of dimensions 150 x 40 x 40 mu m, in a matter of hours.