PRAKASH, Alka, LAIRD, Susan, LI, Tin C and LEDGER, William L (2006). Preliminary prospective study of the endocrinology of conception cycles and early pregnancy in women with antiphospholipid syndrome treated with low molecular weight heparin. Fertility and sterility, 85 (1), 165-170.Full text not available from this repository.
OBJECTIVE : To examine whether there were any differences in the endocrinological profiles during conception cycle and early pregnancy between a control group and women with a history of recurrent miscarriage that was caused by antiphospholipid syndrome and that was treated with aspirin and low molecular weight heparin.
DESIGN : Prospective observational study.
SETTING : Recurrent Miscarriage Clinic, Department of Obstetrics and Gynaecology in a tertiary care centre.
PATIENT(S) : Five women with recurrent pregnancy loss were recruited as cases, whereas another five women having natural cycle donor insemination were used as control.
INTERVENTION(S) : Serial measurement of serum beta-hCG, activin A, and inhibin A was performed from postovulatory day 12 until 11 weeks of gestation.
MAIN OUTCOME MEASURE(S) : Comparison of levels of beta-hCG, activin A, and inhibin A at the time of conception onwards till 11 weeks in the two groups.
RESULT(S) : There were no significant differences between the two groups.
CONCLUSION(S) : There does not appear to be any obvious endocrinological alteration in the conception cycle of women with antiphospholipid syndrome compared with a control group. Furthermore, the initiation of heparin does not produce a significant change in activin A and inhibin A levels.
|Research Institute, Centre or Group:||Biomolecular Sciences Research Centre|
|Depositing User:||Jamie Young|
|Date Deposited:||28 May 2015 10:52|
|Last Modified:||28 May 2015 10:52|
Actions (login required)
Downloads per month over past year