A rationally designed cocatalyst for the Morita–Baylis–Hillman reaction

JONES, Charlotte E.S., TUREGA, Simon M., CLARKE, Matthew L. and PHILP, Douglas (2008). A rationally designed cocatalyst for the Morita–Baylis–Hillman reaction. Tetrahedron Letters, 49 (31), 4666-4669.

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Official URL: http://dx.doi.org/10.1016/j.tetlet.2008.05.037
Link to published version:: 10.1016/j.tetlet.2008.05.037


The application of electronic structure calculations to a key transition state in the reaction manifold of the Morita–Baylis–Hillman reaction allows the design of two bis(thiourea) cocatalysts capable of accelerating this reaction through the hydrogen bond mediated recognition of both the nucleophile and the electrophile.

Item Type: Article
Additional Information: Available online 11 May 2008
Research Institute, Centre or Group: Biomolecular Sciences Research Centre
Identification Number: 10.1016/j.tetlet.2008.05.037
Depositing User: Jamie Young
Date Deposited: 30 Jun 2015 12:32
Last Modified: 30 Jun 2015 12:32
URI: http://shura.shu.ac.uk/id/eprint/10027

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