A rationally designed cocatalyst for the Morita–Baylis–Hillman reaction

JONES, Charlotte E.S., TUREGA, Simon M., CLARKE, Matthew L. and PHILP, Douglas (2008). A rationally designed cocatalyst for the Morita–Baylis–Hillman reaction. Tetrahedron Letters, 49 (31), 4666-4669.

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Official URL: http://dx.doi.org/10.1016/j.tetlet.2008.05.037
Link to published version:: https://doi.org/10.1016/j.tetlet.2008.05.037
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    Abstract

    The application of electronic structure calculations to a key transition state in the reaction manifold of the Morita–Baylis–Hillman reaction allows the design of two bis(thiourea) cocatalysts capable of accelerating this reaction through the hydrogen bond mediated recognition of both the nucleophile and the electrophile.

    Item Type: Article
    Additional Information: Available online 11 May 2008
    Research Institute, Centre or Group - Does NOT include content added after October 2018: Biomolecular Sciences Research Centre
    Identification Number: https://doi.org/10.1016/j.tetlet.2008.05.037
    Page Range: 4666-4669
    Depositing User: Jamie Young
    Date Deposited: 30 Jun 2015 12:32
    Last Modified: 13 Jun 2017 13:29
    URI: http://shura.shu.ac.uk/id/eprint/10027

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