Triphenylarsonium-functionalised gold nanoparticles: potential nanocarriers for intracellular therapeutics

LALWANI, Nikhil, CHEN, Yu-Su, BROOKE, Gemma, CROSS, Neil A., ALLEN, David W., REYNOLDS, Alan, OJEDA, Jesús, TIZZARD, Graham J., COLES, Simon J. and BRICKLEBANK, Neil (2015). Triphenylarsonium-functionalised gold nanoparticles: potential nanocarriers for intracellular therapeutics. Chemical Communications, 51 (19), 4109-4111. [Article]

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Abstract
Two new triphenylarsonium alkylthiolate precursors, a thiosulfate zwitterion and a thioacetate salt, have been structurally characterised and their cytotoxicity evaluated against PC3 cells. The arsonium compounds have been used to prepare gold nanoparticles decorated with triphenylarsonium groups.
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