Linear naphtho-gamma-pyrones : a naturally occurring scaffold of biological importance

BARROW, R. and MCCULLOCH, M. (2009). Linear naphtho-gamma-pyrones : a naturally occurring scaffold of biological importance. Mini-Reviews in Medicinal Chemistry, 9 (3), 273-292.

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Official URL: http://dx.doi.org/10.2174/1389557510909030273
Link to published version:: https://doi.org/10.2174/1389557510909030273

Abstract

The linear naphtho-gamma-pyrone (LNGP) moiety is a naturally occurring scaffold with broad biological activity ranging through antimicrobial, antiviral, insecticidal and anti-estrogenic activity. This review, the first of its kind, surveys the chemical literature in an effort directed toward assembling data that will facilitate the construction of activity profiles associated with this emerging class of compounds. The structural and associated biological information has been presented in tabular format with all structures revealed throughout the document and referencing that will allow the reader to rapidly access the literature pertaining to a specific activity or structural class.

Item Type: Article
Research Institute, Centre or Group - Does NOT include content added after October 2018: Biomedical Research Centre
Identification Number: https://doi.org/10.2174/1389557510909030273
Page Range: 273-292
Depositing User: Users 3084 not found.
Date Deposited: 10 May 2013 09:20
Last Modified: 18 Mar 2021 02:51
URI: https://shura.shu.ac.uk/id/eprint/7014

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