Of mitochondrion and COVID-19.

ALFAROUK, Khalid Omer, ALHOUFIE, Sari TS, HIFNY, Abdelhameed, SCHWARTZ, Laurent, ALQAHTANI, Ali S, AHMED, Samrein, ALQAHTANI, Ali M, ALQAHTANI, Saad S, MUDDATHIR, Abdel Khalig, ALI, Heyam, BASHIR, Adil HH, IBRAHIM, Muntaser E, GRECO, Maria Raffaella, CARDONE, Rosa A, HARGUINDEY, Salvador and RESHKIN, Stephan Joel (2021). Of mitochondrion and COVID-19. Journal of enzyme inhibition and medicinal chemistry, 36 (1), 1258-1267. [Article]

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Abstract
COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction. Therefore, targeting mitochondrion will represent a more rational treatment of COVID-19. The current work outlines how COVID-19's signs and symptoms are related to the mitochondrion. Proper understanding of the underlying causes might enhance the opportunity to treat COVID-19.
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