Efficacy of sodium bicarbonate ingestion strategies for protecting blinding.

GURTON, William H, MATTA, Guilherme G, GOUGH, Lewis A and HURST, Philip (2022). Efficacy of sodium bicarbonate ingestion strategies for protecting blinding. European journal of applied physiology, 122 (12), 255-2563.

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Official URL: https://link.springer.com/article/10.1007/s00421-0...
Open Access URL: https://link.springer.com/content/pdf/10.1007/s004... (Published version)
Link to published version:: https://doi.org/10.1007/s00421-022-05031-0


Sodium bicarbonate (NaHCO3) is a widely researched ergogenic aid, but the optimal blinding strategy during randomised placebo-controlled trials is unknown. In this multi-study project, we aimed to determine the most efficacious ingestion strategy for blinding NaHCO3 research. During study one, 16 physically active adults tasted 0.3 g kg-1 body mass NaHCO3 or 0.03 g kg-1 body mass sodium chloride placebo treatments given in different flavour (orange, blackcurrant) and temperature (chilled, room temperature) solutions. They were required to guess which treatment they had received. During study two, 12 recreational athletes performed time-to-exhaustion (TTE) cycling trials (familiarisation, four experimental). Using a randomised, double-blind design, participants consumed 0.3 g kg-1 body mass NaHCO3 or a placebo in 5 mL kg-1 body mass chilled orange squash/water solutions or capsules and indicated what they believed they had received immediately after consumption, pre-TTE and post-TTE. In study one, NaHCO3 prepared in chilled orange squash resulted in the most unsure ratings (44%). In study two, giving NaHCO3 in capsules resulted in more unsure ratings than in solution after consumption (92 vs 33%), pre-TTE (67 vs. 17%) and post-TTE (50 vs. 17%). Administering NaHCO3 in capsules was the most efficacious blinding strategy which provides important implications for researchers conducting randomised placebo-controlled trials.

Item Type: Article
Uncontrolled Keywords: Dietary supplements; Double-blind; Sports nutrition; Research methods; Dietary supplements; Double-blind; Research methods; Sports nutrition; 1106 Human Movement and Sports Sciences; Sport Sciences
Identification Number: https://doi.org/10.1007/s00421-022-05031-0
Page Range: 255-2563
SWORD Depositor: Symplectic Elements
Depositing User: Symplectic Elements
Date Deposited: 29 Sep 2022 11:02
Last Modified: 12 Oct 2023 09:30
URI: https://shura.shu.ac.uk/id/eprint/30772

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