Testosterone and Covid‐19: An update

YASSIN, Aksam, SABSIGH, Ridwan, AL‐ZOUBI, Raed M., ABOUMARZOUK, Omar M., ALWANI, Mustafa, NETTLESHIP, Joanne and KELLY, Daniel (2022). Testosterone and Covid‐19: An update. Reviews in Medical Virology.

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Abstract

Abstract: There is overwhelming evidence to suggest that male gender is at a higher risk of developing more severe Covid‐19 disease and thus having poorer clinical outcomes. However, the relationship between testosterone (T) and Covid‐19 remains unclear with both protective and deleterious effects on different aspects of the disease suggested. Here, we review the current epidemiological and biological evidence on the role of testosterone in the process of SARS‐CoV‐2 infection and in mediating Covid‐19 severity, its potential to serve as a biomarker for risk stratification and discuss the possibility of T supplementation as a treatment or preventative therapy for Covid‐19.

Item Type:	Article
Additional Information:	** Article version: VoR ** From Wiley via Jisc Publications Router ** Licence for VoR version of this article: http://creativecommons.org/licenses/by-nc/4.0/ **Journal IDs: issn 1052-9276; issn 1099-1654 **Article IDs: publisher-id: rmv2395 **History: published 03-09-2022; accepted 25-08-2022; rev-recd 23-08-2022; submitted 30-06-2022
Uncontrolled Keywords:	REVIEW, prostate, sexual medicine, testosterone
Identification Number:	https://doi.org/10.1002/rmv.2395
SWORD Depositor:	Colin Knott
Depositing User:	Colin Knott
Date Deposited:	05 Sep 2022 15:42
Last Modified:	05 Sep 2022 15:42
URI:	https://shura.shu.ac.uk/id/eprint/30663

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