MALDI imaging of blood and blood provenance in old fingermarks

WITT, Matthias, HEATON, Cameron, KENNEDY, Katie, LANGENBURG, Glenn and FRANCESE, Simona (2021). MALDI imaging of blood and blood provenance in old fingermarks. In: American Society for Mass Spectrometry (ASMS) 2021 Annual Conference, Philadelphia, PA, USA, 31 Oct - 04 Nov 2021. ASMS. (Unpublished)

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Reliable confirmation of the presence of blood in stains and marks is crucial to reconstruct the dynamics of a violent crime. MALDI MS Profiling (MALDI MSP) and MALDI MS Imaging (MALDI MSI) have been shown to be suitable confirmatory tests to this effect [1-4]. However, additional and important information is based on the attribution of the source of blood (animal or human), as a few murder cases in the public domain demonstrate. The Fingermark Research Group at Sheffield Hallam University, recently published on the validation of a MALDI MSP method to detect and distinguish between human and animal blood (down to the animal species level) in enhanced blood marks and stains analyzed in a blind fashion [5] (Figure 1). Here we use a combination of bottom-up proteomics and MALDI MSI to visualize blood of bovine or human origin in 4-year-old fingermarks. These are unused marks originating from the batch of blind samples on which the Kennedy et al. publication [5] was based.

Item Type: Conference or Workshop Item (Poster)
SWORD Depositor: Symplectic Elements
Depositing User: Symplectic Elements
Date Deposited: 24 Mar 2023 15:47
Last Modified: 11 Oct 2023 16:16

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