The relationship between physical activity and severity of covid-19 symptoms in non-hospitalised individuals

MITROPOULOS, Alexandros, GOODWILL, Simon, COPELAND, Robert and KLONIZAKIS, Markos (2022). The relationship between physical activity and severity of covid-19 symptoms in non-hospitalised individuals. European Journal of Public Health: ckac097. [Article]

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Abstract
Background The study explored the relationship between physical activity (PA) behaviour and severity of symptoms in people infected by coronavirus-disease 2019 (COVID-19). Methods Five hundred thirty-three people (16% males, mean age: 45 ± 11 yrs., body mass index (BMI): 23.3 ± 20) took part in the study. All participants were post-COVID-19 infection. An online questionnaire was used to gather data on; participants demographics, comorbidities and treatment, symptomatology of COVID-19, quality of life (QoL) and pre- and post-COVID-19 infection PA. Results Logistic regression revealed that only a high BMI (> 25) increased the severity of (OR 1.01; 95% CI, 0.99-1.03) symptoms from none to mild-to-moderate. Weekly PA behaviour (mins/week) did not affect the primary outcome (symptom severity) as a predictor variable and neither differ (p > 0.05) between symptomatology for both moderate (no symptoms: 181.3 ± 202.1 vs. mild-to-moderate symptoms: 173 ± 210.3), and vigorous (no symptoms: 89.2 ± 147 vs. mild-to-moderate symptoms: 88.9 ± 148.3) PA. QoL (i.e., mobility, self-care, usual activities, pain/discomfort, anxiety/depression, and perceived health) was significantly (p < 0.05) worse post-COVID-19 infection. Conclusions Our findings did not present an association between PA levels and mild-to-moderate COVID-19 symptoms. However, all participants exceeded the lower limit of the WHO-recommended, adult PA dose. This might explain the lack of PA effect, on mild-to-moderate symptoms post-COVID-19 infection. Future studies should explore the effects of PA levels in more severe 3 cases (e.g., hospitalisations) and assess the effectiveness of PA to reduce hospitalisations, and mortality rates as a result of COVID-19 infection.
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