OLUBAMWO, Olubunmi, ONYEKA, Ifeoma N, AREGBESOLA, Alex, RONKAINEN, Kimmo, TIIHONEN, Jari, FÖHR, Jaana and KAUHANEN, Jussi (2017). Association between route of illicit drug administration and hospitalizations for infective endocarditis. SAGE Open Medicine, 5.
|
PDF
Onyeka-AssociationBetweenRoute(VoR).pdf - Published Version Creative Commons Attribution. Download (95kB) | Preview |
Abstract
Objective: This study examined the association between the route of drug administration and being hospitalized for infective endocarditis among 4817 treatment-seeking illicit drug users in Finland. Methods: Cox regression models were used to examine the association between the route of drug administration and infective endocarditis hospitalization, adjusted for age, gender, and homelessness. Cases of infective endocarditis as a primary/main diagnosis were tracked using the 10th version of the International Classification of Disease code I33. Results: In all, 47 persons had a primary diagnosis of infective endocarditis. These 47 persons contributed a total of 95 hospitalizations and their total length of hospital stay was 1393 days. There was a statistically significant difference in hospitalizations between injectors and non-injectors (Log-Rank test p = 0.018). Univariate Cox model showed that injectors had higher hazard or risk for infective endocarditis hospitalization compared to non-injectors (hazard ratio: 2.04, 95% confidence interval: 1.12–3.73, p = 0.020). After adjusting for age, gender, and homelessness in the multivariate model, the elevated hazard among injectors compared to non-injectors remained statistically significant with adjusted hazard ratio of 2.12 (95% confidence interval: 1.11–4.07, p = 0.024). Conclusion: The study findings suggested a need to boost harm reduction measures targeting high-risk injecting and other health behaviors among injecting drug users in order to reduce their hospitalizations for infective endocarditis.
Item Type: | Article |
---|---|
Identification Number: | https://doi.org/10.1177/2050312117740987 |
SWORD Depositor: | Symplectic Elements |
Depositing User: | Symplectic Elements |
Date Deposited: | 13 May 2022 14:37 |
Last Modified: | 13 May 2022 14:37 |
URI: | https://shura.shu.ac.uk/id/eprint/30081 |
Actions (login required)
![]() |
View Item |
Downloads
Downloads per month over past year