Production of fat-based emulsion powder by prilling process using twin-fluid atomizer for controlled release of iron

DUBEY, Bipro and WINDHAB, Erich (2012). Production of fat-based emulsion powder by prilling process using twin-fluid atomizer for controlled release of iron. In: 12th International Conference on Liquid Atomization and Spray Systems, Heidelberg, Germany, 2-6 Sep 2012.

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Abstract

Encapsulation of iron is necessary to supply bioavailable iron to large number of population possess iron deficiency. In the present study, we dispersed the iron solution in a fat matrix of palm stearin, and prepared the simple emulsion (water-in-oil) at 60 ◦C, where fat was a continuous phase. Using that emulsion, we produced fat based emulsion particles through prilling (spray + chilling) process using twin fluid atomizers (internal mixing). We characterized the particle in terms of size and size distribution, and investigated the internal structure of the fatparticles by cryogenic scanning electron microscopy (cryo-SEM) for observing the distribution or homogeneity of dispersed phase. Present study includes mainly the iron release kinetics through the fat matrix of the emulsion particle in an in-vitro gastric system (pH ≈ 2.0 ) as a function of (a) particle size of prills, (b) thickener concentration (polyethylene glycol, PEG) in dispersed phase, (c) droplet size of dispersed phase, (d) mixing properties (Reynolds number, Re), and (e) shelf-life of particles. The release kinetics was explained by the second order kinetics, where we estimated the release kinetic constant, and co-related with the viscosity ratio of dispersed phase to continuous phase, mean particle size of emulsion, and shelf-life of particles. The result showed that the control of the release properties can be obtained by choosing particle size and thickener concentration.

Item Type: Conference or Workshop Item (Paper)
SWORD Depositor: Symplectic Elements
Depositing User: Symplectic Elements
Date Deposited: 30 Apr 2020 13:51
Last Modified: 18 Mar 2021 01:51
URI: https://shura.shu.ac.uk/id/eprint/24970

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