KHUSHHAL, Alaa, NICHOLS, Simon, CARROLL, Sean, ABT, Grant and INGLE, Lee (2019). Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective. PLoS ONE, 14 (6), e0217654. [Article]
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Nichols-InsufficientExerciseIntensity(VoR).pdf - Published Version
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Abstract
Background: In recent years, criticism of the percentage range approach for individualised exercise
prescription has intensified and we were concerned that sub-optimal exercise dose (especially
intensity) may be in part responsible for the variability in the effectiveness of cardiac rehabilitation
(CR) programmes in the United Kingdom (UK). The aim was to investigate the fidelity of a structured
Phase III CR programme, by monitoring and quantifying exercise training intensity.
Design: Observational study.
Methods: The programme comprised 16 sessions over 8 weeks, where patients undertook an
interval, circuit training approach within national guidelines for exercise prescription (40-70% heart
rate reserve [HRR]). All patients wore an Apple Watch (Series 0 or 2, Watch OS2.0.1, Apple Inc.,
California, USA). We compared the mean % heart rate reserve (%HRR) achieved during the
cardiovascular training component (%HRR-CV) of a circuit-based programme, with the %HRR during
the active recovery phases (%HRR-AR) in a randomly selected cohort of patients attending standard
CR. We then compared the mean %HRR-CV achieved with the minimal exercise intensity threshold
during supervised exercise (40% HRR) recommended by national governing bodies.
Results: Thirty cardiac patients (83% male; mean age [SD] 67 [10] years; BMI 28.3 [4.6] kg∙m-2
) were
recruited. We captured 332 individual training sessions. The mean %HRR-CV and %HRR-AR were 37
(10) %, and 31 (13) %, respectively. There was weak evidence to support the alternative hypothesis
of a difference between the %HRR-CV and 40% HRR. There was very strong evidence to accept the
alternative hypothesis that the mean %HRR-AR was lower than the mean %HRR-CV (median
standardised effect size 1.1 (95%CI: 0.563 to 1.669) with a moderate to large effect.
Conclusion: Mean exercise training intensity was below the lower limit of the minimal training
intensity guidelines for a Phase III CR programme. These findings may be in part responsible for
previous reports highlighting the significant variability in effectiveness of UK CR services and poor
CRF improvements observed from several prior investigations.
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