Multi-way optimal control of a benchmark fed-batch fermentation process

A novel optimal control algorithm is presented for application to batch processes. The algorithm utilizes a linear model of the process that is identified using multi-way partial least squares. This linear model is used within an optimal control law to regulate the productivity of the batch by manipulating the substrates that are fed into the fermentation vessel. The proposed control algorithm is successfully applied to a benchmark fed-batch fermentation process and its performance compared with alternative control algorithms that have been applied to this application in the past. The proposed controller is found to compare favourably with these alternative algorithms.