Automated Glaucoma Detection Using Hybrid Feature Extraction in Retinal Fundus Images

RAMA KRISHNAN M, Muthu and FAUST, Oliver (2012). Automated Glaucoma Detection Using Hybrid Feature Extraction in Retinal Fundus Images. Journal of Mechanics in Medicine and Biology, 13 (1), 1350011-1350032.

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Glaucoma is one of the most common causes of blindness. Robust mass screening may help to extend the symptom-free life for affected patients. To realize mass screening requires a cost-effective glaucoma detection method which integrates well with digital medical and administrative processes. To address these requirements, we propose a novel low cost automated glaucoma diagnosis system based on hybrid feature extraction from digital fundus images. The paper discusses a system for the automated identification of normal and glaucoma classes using higher order spectra (HOS), trace transform (TT), and discrete wavelet transform (DWT) features. The extracted features are fed to a support vector machine (SVM) classifier with linear, polynomial order 1, 2, 3 and radial basis function (RBF) in order to select the best kernel for automated decision making. In this work, the SVM classifier, with a polynomial order 2 kernel function, was able to identify glaucoma and normal images with an accuracy of 91.67%, and sensitivity and specificity of 90% and 93.33%, respectively. Furthermore, we propose a novel integrated index called Glaucoma Risk Index (GRI) which is composed from HOS, TT, and DWT features, to diagnose the unknown class using a single feature. We hope that this GRI will aid clinicians to make a faster glaucoma diagnosis during the mass screening of normal/glaucoma images.

Item Type: Article
Identification Number:
Page Range: 1350011-1350032
Depositing User: Oliver Faust
Date Deposited: 15 Aug 2017 08:31
Last Modified: 18 Mar 2021 05:55

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