CROSS, N A, KELLOCK, D J, KINGHORN, G R, TARAKTCHOGLOU, M, BATAKI, E, OXLEY, K M, HAWKEY, P M and ELEY, A (1999). Antimicrobial susceptibility testing of Chlamydia trachomatis using a reverse transcriptase PCR-based method. Antimicrobial agents and chemotherapy, 43 (9), 2311-2313.
Full text not available from this repository.Abstract
The conventional method for antimicrobial susceptibility testing of Chlamydia trachomatis is subjective and potentially misleading. We have developed a reverse transcriptase PCR (RT-PCR)-based method which is more sensitive and less subjective than the conventional method. Using 16 strains of C. trachomatis in triplicate assays, we found the RT-PCR method consistently more sensitive than the conventional technique for all eight antimicrobials tested, with resultant MICs determined by RT-PCR ranging from 1.6-fold higher (erythromycin) to >/=195-fold higher (amoxicillin).
Item Type: | Article |
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Research Institute, Centre or Group - Does NOT include content added after October 2018: | Biomedical Research Centre |
Page Range: | 2311-2313 |
Depositing User: | Jamie Young |
Date Deposited: | 03 Jun 2015 08:14 |
Last Modified: | 18 Mar 2021 18:45 |
URI: | https://shura.shu.ac.uk/id/eprint/9968 |
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