Interleukin-1 receptor antagonist and interleukin-1 beta polymorphisms in women with recurrent miscarriage.

LINJAWI, Sabah, LI, Tin-Chiu, LAIRD, Susan and BLAKEMORE, Alexandra (2005). Interleukin-1 receptor antagonist and interleukin-1 beta polymorphisms in women with recurrent miscarriage. Fertility and sterility, 83 (5), 1549-1552.

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Official URL: http://dx.doi.org/10.1016/j.fertnstert.2004.10.052
Link to published version:: 10.1016/j.fertnstert.2004.10.052

Abstract

Genotypes and allele distributions for the interleukin (IL)-1beta -511 C/T and the IL-1 receptor antagonist gene intron 2 tandem repeat polymorphisms were compared in 206 women with recurrent miscarriage and a control population. No significant differences were observed between the distributions of IL-1beta or IL-1 receptor antagonist gene alleles in either the recurrent miscarriage group as a whole or when divided according to the cause of recurrent miscarriage compared with controls, which suggests that variation in the IL-1 receptor antagonist gene and IL-1beta genes individually does not play a role in susceptibility to recurrent miscarriage.

Item Type: Article
Research Institute, Centre or Group: Biomolecular Sciences Research Centre
Identification Number: 10.1016/j.fertnstert.2004.10.052
Depositing User: Jamie Young
Date Deposited: 28 May 2015 10:47
Last Modified: 28 May 2015 10:47
URI: http://shura.shu.ac.uk/id/eprint/9908

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