BRADSHAW, Richard, BLEAY, S, CLENCH, Malcolm and FRANCESE, Simona (2014). Direct detection of blood in fingermarks by MALDI MS profiling and imaging. Science & justice, 54 (2), 110-7.Full text not available from this repository.
The determination of the presence of blood in fingermarks constitutes important intelligence in a criminal investigation as it helps to reconstruct the events that have taken place at a scene of crime. Various methodologies have been reported and are currently employed for the detection of the presence of blood including optical, spectroscopic and chemical development approaches. However, most methods only give an indication that blood may be present and, therefore, these methods are described as presumptive tests. Here we show the use of Matrix-Assisted Laser Desorption Ionisation Mass Spectrometry Profiling and Imaging (MALDI MSP and MALDI MSI) for the determination of the presence of blood in fingermarks by specifically detecting the molecules of haem and haemoglobin through their mass-to-charge ratios. Furthermore, preliminary experiments are shown which demonstrate that this technology is compatible with other methods currently employed for enhancing fingermarks in blood (or contaminated by blood). The application of the developed protocols to a crime scene blood trace, demonstrates the feasibility of using this technology in routine casework. These findings open up a new line of research for the development of robust MALDI MSP and MALDI MSI protocols for the detection and chemical imaging of bloodied marks.
|Research Institute, Centre or Group:||Biomolecular Sciences Research Centre|
|Depositing User:||Louise Vickers|
|Date Deposited:||31 Oct 2014 14:37|
|Last Modified:||31 Oct 2014 14:37|
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