Fractionated marine invertebrate extract libraries for drug discovery

BUGNI, Tim S., HARPER, Mary Kay, MCCULLOCH, Malcolm W.B., REPPART, Jason and IRELAND, Chris M. (2008). Fractionated marine invertebrate extract libraries for drug discovery. Molecules, 13 (6), 1372-1383.

Full text not available from this repository.
Official URL: http://dx.doi.org/10.3390/molecules13061372
Link to published version:: https://doi.org/10.3390/molecules13061372
Related URLs:

    Abstract

    The high-throughput screening and drug discovery paradigm has necessitated a change in preparation of natural product samples for screening programs. In an attempt to improve the quality of marine natural products samples for screening, several fractionation strategies were investigated. The final method used HP20SS as a solid support to effectively desalt extracts and fractionate the organic components. Additionally, methods to integrate an automated LCMS fractionation approach to shorten discovery time lines have been implemented.

    Item Type: Article
    Research Institute, Centre or Group - Does NOT include content added after October 2018: Biomolecular Sciences Research Centre
    Identification Number: https://doi.org/10.3390/molecules13061372
    Page Range: 1372-1383
    Depositing User: Users 3084 not found.
    Date Deposited: 10 May 2013 09:23
    Last Modified: 10 May 2013 09:23
    URI: http://shura.shu.ac.uk/id/eprint/7015

    Actions (login required)

    View Item View Item

    Downloads

    Downloads per month over past year

    View more statistics