Targeting of Hypoxia in AQ4N-treated Tumour Xenografts by MALDI-Ion Mobility Separation-Mass Spectrometry Imaging.

DJIDJA, Marie-Claude, FRANCESE, Simona, CLAUDE, Emmanuelle, LOADMAN, Paul, SUTTON, Chris, SHYNDER, Steve, COOPER, Patricia, PATTERSON, Laurence H, CAROLAN, Vikki and CLENCH, Malcolm (2013). Targeting of Hypoxia in AQ4N-treated Tumour Xenografts by MALDI-Ion Mobility Separation-Mass Spectrometry Imaging. Current Analytical Chemistry, 9 (2), 212-225.

Full text not available from this repository.
Official URL: DOI: http://dx.doi.org.lcproxy.shu.ac.uk/10.2174/1...
Link to published version:: 10.2174/157341113805218884

Abstract

In situ investigation and characterisation of hypoxia-related protein markers in AQ4N treated tumour xenografts. MALDI-IMS-MSI enabled the visualisation of the distribution of AQ4N and AQ4 within the tissue sections, hence the selective localisation hypoxic tissue regions. Protein distribution and identification were obtained directly from AQ4N treated and non treated tumour tissue sections after in situ digestion.

Item Type: Article
Research Institute, Centre or Group: Biomedical Research Centre
Identification Number: 10.2174/157341113805218884
Depositing User: Rebecca Jones
Date Deposited: 23 Jul 2012 16:19
Last Modified: 20 Mar 2013 15:43
URI: http://shura.shu.ac.uk/id/eprint/5550

Actions (login required)

View Item

Downloads

Downloads per month over past year

View more statistics