Biochemistry of envenomation

KAUR, Prameet, GHARIWALA, Vibha, YEO, Kun Song, TAN, Hui Zhing, TAN, Jian Chye Sam, ARMUGAM, Arunmozhiarasi, STRONG, Peter and JEYASEELAN, Kandiah (2012). Biochemistry of envenomation. Current Advances in Clinical Chemistry, 57, 187-252.

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Venoms and toxins are of significant interest due to their ability to cause a wide range of pathophysiological conditions that can potentially result in death. Despite their wide distribution among plants and animals, the biochemical pathways associated with these pathogenic agents remain largely unexplored. Impoverished and underdeveloped regions appear especially susceptible to increased incidence and severity due to poor socioeconomic conditions and lack of appropriate medical treatment infrastructure. To facilitate better management and treatment of envenomation victims, it is essential that the biochemical mechanisms of their action be elucidated. This review aims to characterize downstream envenomation mechanisms by addressing the major neuro-, cardio-, and hemotoxins as well as ion-channel toxins. Because of their use in folk and traditional medicine, the biochemistry behind venom therapy and possible implications on conventional medicine will also be addressed.

Item Type: Article
Research Institute, Centre or Group - Does NOT include content added after October 2018: Biomedical Research Centre
Identification Number:
Page Range: 187-252
Depositing User: Rebecca Jones
Date Deposited: 21 Jun 2012 14:03
Last Modified: 19 Mar 2021 00:15

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