Separation of nicotine metabolites by capillary zone electrophoresis and capillary zone electrophoresis/mass spectrometry

PALMER, M. E., SMITH, R. F., CHAMBERS, K. and TETLER, L. W. (2000). Separation of nicotine metabolites by capillary zone electrophoresis and capillary zone electrophoresis/mass spectrometry. Rapid communications in mass spectrometry, 15 (3), 224-231.

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Link to published version:: 10.1002/1097-0231(20010215)15:3<224::AID-RCM213>3.0.CO;2-Z

Abstract

The use of capillary zone electrophoresis (CZE) and capillary zone electrophoresis/mass spectrometry (CZE/MS) has been demonstrated, in principle, for the separation of nicotine and nicotine metabolites. The buffer system developed for separation and detection by CZE/UV was modified for use in CZE/MS analysis. Several of the metabolites are isobaric and tandem mass spectrometric (MS/MS) techniques have been used to differentiate such analytes.

Item Type: Article
Research Institute, Centre or Group: Biomedical Research Centre
Identification Number: 10.1002/1097-0231(20010215)15:3<224::AID-RCM213>3.0.CO;2-Z
Depositing User: Ann Betterton
Date Deposited: 11 Mar 2008
Last Modified: 09 Dec 2009 18:23
URI: http://shura.shu.ac.uk/id/eprint/411

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