A knowledge-based electrocardiogram-monitoring system for detection of the onset of nocturnal hypoglycaemia in type 1 diabetic patients

ALEXAKIS, M, RODRIGUES, Marcos, SAATCHI, Reza, NYONGESA, H O, DAVIES, C, IRELAND, R H, HARRIS, N D and HELLER, S R (2009). A knowledge-based electrocardiogram-monitoring system for detection of the onset of nocturnal hypoglycaemia in type 1 diabetic patients. In: MURRAY, A, (ed.) 2006 33rd Conference on Computers in Cardiology. IEEE.

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Abstract

Nocturnal hypoglycaemia has been implicated in the sudden deaths of young people with diabetes. Experimental hypoglycaemia has been found to prolong the ventricular repolarisation and to affect the T wave morphology. It is postulated that abnormally low blood glucose could in certain circumstances, be responsible for the development of a fatal cardiac arrhythmia. We have designed a monitoring and alarm system for detection of the onset of spontaneous nocturnal hypoglycaemia through monitoring of the electrocardiogram. The system incorporates expert- knowledge in the form of a rule-base. It performs monitoring of two ECG features and raises alarms if abnormalities are detected corresponding to hypoglycaemia. The top performance of the system is 100% and 91.30% for sensitivity and specificity respectively. This study supports the hypothesis proposing a relationship between cardiac function and abnormally low blood glucose.

Item Type: Book Section
Research Institute, Centre or Group: Cultural Communication and Computing Research Institute > Communication and Computing Research Centre
Depositing User: Hilary Ridgway
Date Deposited: 28 Oct 2011 09:25
Last Modified: 28 Oct 2011 09:25
URI: http://shura.shu.ac.uk/id/eprint/3982

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