Of mitochondrion and COVID-19.

ALFAROUK, Khalid Omer, ALHOUFIE, Sari TS, HIFNY, Abdelhameed, SCHWARTZ, Laurent, ALQAHTANI, Ali S, AHMED, Samrein, ALQAHTANI, Ali M, ALQAHTANI, Saad S, MUDDATHIR, Abdel Khalig, ALI, Heyam, BASHIR, Adil HH, IBRAHIM, Muntaser E, GRECO, Maria Raffaella, CARDONE, Rosa A, HARGUINDEY, Salvador and RESHKIN, Stephan Joel (2021). Of mitochondrion and COVID-19. Journal of enzyme inhibition and medicinal chemistry, 36 (1), 1258-1267.

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Official URL: http://dx.doi.org/10.1080/14756366.2021.1937144
Open Access URL: https://www.tandfonline.com/doi/epdf/10.1080/14756... (Published version)
Link to published version:: https://doi.org/10.1080/14756366.2021.1937144


COVID-19, a pandemic disease caused by a viral infection, is associated with a high mortality rate. Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction. Therefore, targeting mitochondrion will represent a more rational treatment of COVID-19. The current work outlines how COVID-19's signs and symptoms are related to the mitochondrion. Proper understanding of the underlying causes might enhance the opportunity to treat COVID-19.

Item Type: Article
Uncontrolled Keywords: Mitochondria; Humans; Antiviral Agents; COVID-19; SARS-CoV-2; COVID-19 Drug Treatment; COVID-19; cytokine storm; inflammation; mitochondrion; treatment; Antiviral Agents; COVID-19; Humans; Mitochondria; SARS-CoV-2; COVID-19 Drug Treatment; 0304 Medicinal and Biomolecular Chemistry; 0601 Biochemistry and Cell Biology; Medicinal & Biomolecular Chemistry; 3404 Medicinal and biomolecular chemistry
Identification Number: https://doi.org/10.1080/14756366.2021.1937144
Page Range: 1258-1267
SWORD Depositor: Symplectic Elements
Depositing User: Symplectic Elements
Date Deposited: 18 Apr 2024 10:45
Last Modified: 18 Apr 2024 11:00
URI: https://shura.shu.ac.uk/id/eprint/33569

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