Pharmacological treatments of fibromyalgia: Do complex conditions need complex therapies?

LAWSON, K. (2008). Pharmacological treatments of fibromyalgia: Do complex conditions need complex therapies? Drug Discovery Today, 13 (7-8), 333-340.

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Link to published version:: 10.1016/j.drudis.2008.01.004

Abstract

Fibromyalgia (FM) is a chronic pain condition, with auxiliary symptoms, such as sleep disturbances and fatigue. Although many of the mechanisms of action targeted by the drugs used to treat FM have been focused to the management of single symptoms, drugs (e.g. pregabalin, duloxetine) have now been identified that demonstrate a multidimensional effect. However, such drugs often fail to demonstrate acceptable efficacy in the majority of the patient population. Thus, the mechanisms of action of the drugs studied as treatments for FM are either identifying subgroups within the pathophysiology of the condition or suggesting that a mechanism of action that will offer universal efficacy has, as yet, to be identified.

Item Type: Article
Research Institute, Centre or Group: Biomedical Research Centre
Identification Number: 10.1016/j.drudis.2008.01.004
Depositing User: Sarah Ward
Date Deposited: 25 Feb 2011 16:38
Last Modified: 25 Feb 2011 16:38
URI: http://shura.shu.ac.uk/id/eprint/3228

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