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PRINCIVALLE, Alessandra P. (2021). GABAB Receptors in Neurodegeneration. In: Current Topics in Behavioral Neurosciences. Current Topics in Behavioral Neurosciences . Springer Berlin Heidelberg.
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Princivalle-GABAB_Recptors_Neurodegeneration(AM).pdf - Accepted Version All rights reserved. Download (676kB) | Preview |
Abstract
GABA is the main inhibitory neurotransmitter in the mammalian central nervous system (CNS) and acts via metabotropic GABAB receptors. Neurodegenerative diseases are a major burden and affect an ever increasing number of humans. The actual therapeutic drugs available are partially effective to slow down the progression of the diseases, but there is a clear need to improve pharmacological treatment thus find alternative drug targets and develop newer pharmaco-treatments. This chapter is dedicated to reviewing the latest evidence about GABAB receptors and their inhibitory mechanisms and pathways involved in the neurodegenerative pathologies.
| Item Type: | Book Section |
|---|---|
| Additional Information: | ISSN Online: 1866-3389 ISSN Print : 1866-3370 Invited contribution to a book writing a chapter |
| Uncontrolled Keywords: | Biomolecular Sciences Research Centre; Alzheimer’s disease; GABAB receptors; Hippocampal sclerosis; Neurodegenerative diseases; Parkinson’s disease; Temporal lobe epilepsy. |
| Identification Number: | https://doi.org/10.1007/7854_2021_222 |
| SWORD Depositor: | Symplectic Elements |
| Depositing User: | Symplectic Elements |
| Date Deposited: | 06 May 2021 15:59 |
| Last Modified: | 17 Mar 2022 01:18 |
| URI: | https://shura.shu.ac.uk/id/eprint/28618 |
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