Exercise interventions and health-related quality of life after stroke and TIA: a systematic review and meta-analysis

ALI, Ali, TABASSUM, Dina, BAIG, Sheharya S, MOYLE, Bethany, REDGRAVE, Jessica, NICHOLS, Simon, MCGREGOR, Gordon, EVANS, Katherine, TOTTON, Nikki, COOPER, Cindy and ARSHAD, Majid (2021). Exercise interventions and health-related quality of life after stroke and TIA: a systematic review and meta-analysis. Stroke.

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    Abstract

    Exercise interventions have been shown to help physical fitness, walking and balance after stroke, but data is lacking on whether such interventions lead to improvements in health-related quality of life (HRQoL). In this systematic review and meta-analysis, thirty randomised controlled trials (n=1,836 patients) were found from PubMed, OVID MEDLINE, Web of Science, CINAHL, SCOPUS, The Cochrane Library and TRIP databases when searched from 1966 to Feb 2020, that examine the effects of exercise interventions on HRQoL after strokem or transient ischaemic attack (TIA). Exercise interventions resulted in small to moderate beneficial effects on HRQoL at intervention end (standardised mean difference (SMD) -0.23; 95% CI -0.40 to -0.07) that appeared to diminish at longer term follow up (SMD -0.11; 95%CI -0.26 to 0.04). Exercise was associated with moderate improvements in physical health (SMD -0.33; 95% CI -0.61 to -0.04) and mental health (SMD -0.29; 95% CI -0.49 to -0.09) domains of HRQoL while effects on social or cognitive composites showed little difference. Interventions that were initiated within 6 months, lasted at least 12 weeks in duration, involved at least 150 minutes per week, and included resistance training appeared most effective. Exercise can lead to moderate beneficial effects on HRQoL and should be considered an integral part of stroke rehabilitation

    Item Type: Article
    Uncontrolled Keywords: 1102 Cardiorespiratory Medicine and Haematology; 1103 Clinical Sciences; 1109 Neurosciences; Neurology & Neurosurgery
    SWORD Depositor: Symplectic Elements
    Depositing User: Symplectic Elements
    Date Deposited: 28 Mar 2021 12:51
    Last Modified: 29 Mar 2021 08:00
    URI: http://shura.shu.ac.uk/id/eprint/28447

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