Emerging applications in mass spectrometry imaging; enablers and roadblocks

RUSSO, C., HEATON, C., FLINT, L., VOLOACA, Oana, HAYWOOD-SMALL, Sarah, CLENCH, Malcolm, FRANCESE, Simona and COLE, Laura (2020). Emerging applications in mass spectrometry imaging; enablers and roadblocks. Journal of Spectral Imaging, 9, 1-21.

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Official URL: https://www.impopen.com/jsi-abstract/I09_a13
Open Access URL: https://www.impopen.com/download.php?code=I09_a13 (Published version)
Link to published version:: https://doi.org/10.1255/jsi.2020.a13
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    Abstract

    © 2020 The Authors. Mass spectrometry imaging (MSI) is a powerful and versatile technique able to investigate the spatial distribution of multiple non-labelled endogenous and exogenous analytes simultaneously, within a wide range of samples. Over the last two decades, MSI has found widespread application for an extensive range of disciplines including pre-clinical drug discovery, clinical applications and human identification for forensic purposes. Technical advances in both instrumentation and software capabilities have led to a continual increase in the interest in MSI; however, there are still some limitations. In this review, we discuss the emerging applications in MSI that significantly impact three key areas of mass spectrometry (MS) research—clinical, pre-clinical and forensics—and roadblocks to the expansion of use of MSI in these areas.

    Item Type: Article
    Identification Number: https://doi.org/10.1255/jsi.2020.a13
    Page Range: 1-21
    SWORD Depositor: Symplectic Elements
    Depositing User: Symplectic Elements
    Date Deposited: 25 Nov 2020 15:45
    Last Modified: 17 Mar 2021 20:00
    URI: http://shura.shu.ac.uk/id/eprint/27669

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