Exercise and Polycystic Ovary Syndrome.

WOODWARD, Amie, KLONIZAKIS, Markos and BROOM, David (2020). Exercise and Polycystic Ovary Syndrome. In: XIAO, Junjie, (ed.) Physical Exercise for Human Health. Advances in Experimental Medicine and Biology, 1228 . Springer, 123-136.

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Link to published version:: https://doi.org/10.1007/978-981-15-1792-1_8
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    Polycystic ovary syndrome (PCOS) is a complex endocrinopathy affecting both the metabolism and reproductive system of women of reproductive age. Prevalence ranges from 6.1-19.9% depending on the criteria used to give a diagnosis. PCOS accounts for approximately 80% of women with anovulatory infer-tility, and causes disruption at various stages of the reproductive axis. Evidence suggests lifestyle modification should be the first line of therapy for women with PCOS. Several studies have examined the impact of exercise interventions on reproductive function, with results indicating improvements in menstrual and/or ovulation frequency following exercise. Enhanced insulin sensitivity underpins the mechanisms of how exercise restores reproductive function. Women with PCOS typically have a cluster of metabolic abnormalities that are risk factors for CVD. There is irrefutable evidence that exercise mitigates CVD risk factors in women with PCOS. The mechanism by which exercise improves many CVD risk factors is again associated with improved insulin sensitivity and decreased hyperinsulinemia. In addition to cardiometabolic and reproductive complications, PCOS has been associated with an increased prevalence of mental health disorders. Exercise improves psychological well-being in women with PCOS, dependent on certain physiological factors. An optimal dose-response relationship to exercise in PCOS may not be feasible because of the highly individualised characteristics of the disorder. Guidelines for PCOS suggest at least 150 min of physical activity per week. Evidence confirms that this should form the basis of any clinician or healthcare professional prescription.

    Item Type: Book Section
    Additional Information: Series ISSN 0065-2598
    Uncontrolled Keywords: Cardiovascular disease; Exercise; Physical activity; Polycystic ovary syndrome; Reproductive health; 11 Medical and Health Sciences; General & Internal Medicine
    Identification Number: https://doi.org/10.1007/978-981-15-1792-1_8
    Page Range: 123-136
    SWORD Depositor: Symplectic Elements
    Depositing User: Symplectic Elements
    Date Deposited: 14 May 2020 13:22
    Last Modified: 14 May 2020 13:30
    URI: http://shura.shu.ac.uk/id/eprint/26323

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