KHATAB, Khaled, INTHAWONG, Rungkarn, WHITFIELD, Malcolm, COLLINS, Karen, RAHEEM, Maruf A and ISMAIL, Mubarak (2019). Application of Cardiovascular disease (CVD) risk assessment equations to the Thai population. Biostatistics and Epidemiology International Journal.

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Abstract
Objective: The objectives of this study are: 1.) To calculate the probability of Cardiovascular Disease (CVD) events by applying three different equations, which are: the AsiaPacific Cohort Study (APCS) equation, the FraminghamAsia equation and the original Framingham equation, to the individual risk factors data from the NHESIV, Thailand. 2) To estimate the number of 810 years CVD events. 3) To validate and identify the most suitable CVD risk equations for the Thai population. The individual risk factors from the NHESIV dataset was entered into a Microsoft Excel spreadsheet as the baseline population. Methods: AsiaPacific Collaborative Cohort Study (APCCS) equations, the FraminghamAsia equation and the original Framingham equation, are applied to calculate the probability of 8 to 10 years CVD events by age groups and gender. The CVD events in this analysis refer to all fatal and nonfatal CVD events (ICD10, I00I99), which include Ischemic heart disease (IHD) (ICD10, I20I25) and stroke (ICD10, I60I69). Results: The 4th National Health Examination Survey IV 2009 (NHESIV) dataset has been entered into a Microsoft Excel spreadsheet as the baseline population. APCCS, the FraminghamAsia and the original Framingham equations, were applied to the NHESIV dataset. The APCCS equation calculated the average 8years probability of getting CVD as 8.3% in men and 7.8% in women. The 8year likelihood of CVD in the FraminghamAsia equation was 7.2% in men and 8.1% in women. The original Framingham equation showed the highest probability of 10years CVD which were 18.8% in men and 11.1% in women. Conclusions: The original Framingham equation overestimated the risk of CVD in the Thai population in all age groups. The AsiaPacific Cohort Study (APCCS) and the FraminghamAsia equations, both performed better estimation than the original Framingham equation in both men and women.
Item Type:  Article 

SWORD Depositor:  Symplectic Elements 
Depositing User:  Symplectic Elements 
Date Deposited:  04 Feb 2019 11:35 
Last Modified:  04 Feb 2019 11:35 
URI:  http://shura.shu.ac.uk/id/eprint/23940 
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