A preliminary study comparing the endometrial expression of inhibin, activin and follistatin in women with a history of implantation failure after IVF treatment and a control group

PRAKASH, A., TUCKERMAN, E., LAIRD, S., OLA, B., LI, T. C. and LEDGER, W. L. (2008). A preliminary study comparing the endometrial expression of inhibin, activin and follistatin in women with a history of implantation failure after IVF treatment and a control group. British journal of obstetrics and gynaecology, 115 (4), 532-536.

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Link to published version:: 10.1111/j.1471-0528.2007.01624.x

Abstract

The aim of this study was to evaluate the expression of activin: beta A and beta B subunit and follistatin in endometrium of women with implantation failure (n = 10) and compare it with a fertile control group (n = 7). Immunohistochemical staining intensity for follistatin in the endometrial glandular epithelium from women with implantation failure were significantly lower than that in control women (P = 0.03). The decreased expression of follistatin in epithelial cells in the endometrium of women with implantation failure after in vitro fertilisation (IVF) may suggest that follistatin may play a role in the implantation process.

Item Type: Article
Research Institute, Centre or Group: Biomedical Research Centre
Identification Number: 10.1111/j.1471-0528.2007.01624.x
Depositing User: Sarah Ward
Date Deposited: 24 Jun 2010 16:33
Last Modified: 24 Jun 2010 16:33
URI: http://shura.shu.ac.uk/id/eprint/2139

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