Gluten ataxia

HADJIVASSILIOU, M., SANDERS, D. S., WOODROOFE, N., WILLIAMSON, C. and GRÜNEWALD, R. A. (2008). Gluten ataxia. The Cerebellum, 7 (3), 494-498.

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Link to published version:: 10.1007/s12311-008-0052-x

Abstract

Gluten ataxia is an immune-mediated disease triggered by the ingestion of gluten in genetically susceptible individuals. It should be considered in the differential diagnosis of all patients with idiopathic sporadic ataxia. Early diagnosis and treatment with a gluten free diet can improve ataxia and prevent its progression. Readily available and sensitive markers of gluten ataxia include antigliadin antibodies. IgA deposits against TG2 in the small bowel and at extraintestinal sites are proving to be additional reliable and perhaps more specific markers of the whole spectrum of gluten sensitivity. They may also hold the key to its pathogenesis.

Item Type: Article
Research Institute, Centre or Group: Biomedical Research Centre
Identification Number: 10.1007/s12311-008-0052-x
Depositing User: Sarah Ward
Date Deposited: 04 Jun 2010 14:04
Last Modified: 04 Jun 2010 14:04
URI: http://shura.shu.ac.uk/id/eprint/2115

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