Comparison of MRI and DXA to measure muscle size and age-related atrophy in thigh muscles.

MADEN-WILKINSON, Tom, DEGENS, H, JONES, D A and MCPHEE, J S (2013). Comparison of MRI and DXA to measure muscle size and age-related atrophy in thigh muscles. Journal of musculoskeletal & neuronal interactions, 13 (3), 320-8.

[img]
Preview
PDF
Maden-Wilkinson JMNI 2013.pdf - Published Version
Creative Commons Attribution Non-commercial Share Alike.

Download (3MB) | Preview
Official URL: http://www.ismni.org/jmni/Archive.php?year=2013
Related URLs:

    Abstract

    OBJECTIVES Magnetic resonance imaging (MRI) and dual-energy x-ray absorptiometry (DXA) were used to examine the thigh lean mass in young and old men and women. METHODS A whole-body DXA scan was used to estimate thigh lean mass in young (20 men; 22.4±3.1y; 18 women; 22.1±2.0y) and older adults (25 men; 72.3±4.9y; 28 women; 72.0±4.5y). Thigh lean mass determined with a thigh scan on the DXA or full thigh MRI scans were compared. RESULTS Although the thigh lean mass quantified by DXA and MRI in young and older participants were correlated (R(2)=0.88; p<0.001) the magnitude of the differences in thigh lean mass between young and old was smaller with DXA than MRI (old vs. young men 79.5±13.1% and 73.4±11.2%; old vs. young women 88.6±11.8% and 79.4±12.3%, respectively). Detailed analysis of MRI revealed 30% smaller quadriceps muscles in the older than young individuals, while the other thigh muscles were only 18% smaller. CONCLUSIONS DXA underestimates the age-related loss of thigh muscle mass in comparison to MRI. The quadriceps muscles were more susceptible to age-related atrophy compared with other thigh muscles.

    Item Type: Article
    Research Institute, Centre or Group - Does NOT include content added after October 2018: Centre for Sport and Exercise Science
    Page Range: 320-8
    Depositing User: Tom Maden-Wilkinson
    Date Deposited: 17 Jan 2018 11:38
    Last Modified: 27 Jan 2018 00:53
    URI: http://shura.shu.ac.uk/id/eprint/17531

    Actions (login required)

    View Item View Item

    Downloads

    Downloads per month over past year

    View more statistics