MALDI mass spectrometry profiling and imaging applied to the analysis of latent fingermarks

BRADSHAW, Robert (2017). MALDI mass spectrometry profiling and imaging applied to the analysis of latent fingermarks. In: COLE, Laura, (ed.) Imaging mass spectrometry : methods and protocols. Methods in Molecular Biology (1618). New York, Humana Press, 149-163.

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Latent fingermarks are derived from a transfer of material from the fingertips to a surface upon contact. Traditionally, fingermarks are employed for biometric identification of individuals based on matching of the pattern of the ridges. However, in recent years, there has been a stark increase in the use of advanced analytical techniques in order to obtain additional information, specifically the chemical composition of the residue. Understanding the complexity of the endogenous and exogenous content of fingermarks could be extremely useful in allowing further development of enhancement techniques currently used in forensic scenarios by identifying potential target molecules. This chemical information could also potentially provide invaluable information on the lifestyle of an individual, including their activities prior to depositing a mark. An analytical tool that has gained notable popularity in this novel area of research is matrix-assisted laser desorption/ionisation mass spectrometry (MALDI MS). This technique can either be employed for rapid chemical profiling or imaging of fingermarks to detect chemical species contained within the residue, with the latter also allowing for physical reconstruction of the fingermark ridges. This chapter will provide an overview of the protocols employed to allow for both MALDI MS profiling and imaging analysis of latent fingermarks, specifically covering the types of fingermarks employed and techniques used to deposit matrices onto samples.

Item Type: Book Section
Additional Information: Book series ISSN: 1064-3745
Research Institute, Centre or Group - Does NOT include content added after October 2018: Biomedical Research Centre
Identification Number:
Page Range: 149-163
Depositing User: Carmel House
Date Deposited: 18 Jul 2017 14:08
Last Modified: 18 Mar 2021 00:50

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