Investigating patient recruitment to radiotherapy clinical trials

THOMPSON, Emma and CLARKSON, Melanie (2016). Investigating patient recruitment to radiotherapy clinical trials. Journal of Radiotherapy in Practice, 15 (3), 232-238.

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Link to published version:: 10.1017/S1460396916000224


Radiotherapy randomised controlled trials provide evidence to support the development of new techniques and dose/fractionation regimens. Some radiotherapy trials have previously had to close early or revise targets due to low recruitment rates. Many authors have recommended research into recruitment strategies for many areas of medicine, however little work has been carried out in the specific field of radiotherapy. Using a survey of research radiographers followed by radiotherapy patient interviews, this project provides perspectives on motives for patient participation in radiotherapy clinical trials, and how to best support people through this decision-making process. The main factors influencing participation identified by the radiographers were altruism, treatment fatigue and concerns about the trial arms, lack of resources and lack of commitment from some medical colleagues. For patients the main factors were mainly emotional; altruism, and fears for efficacy of different trial arms featured, with requests for timely communication of trial information. We recommend that strategies should be offered proactively to support patients through the decision-making process when considering trial participation. Research radiographers are ideally qualified to offer support and expert knowledge to these patients.

Item Type: Article
Identification Number: 10.1017/S1460396916000224
Depositing User: Margaret Boot
Date Deposited: 19 Sep 2016 14:47
Last Modified: 19 Sep 2016 14:47

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