SÖKMEN, Münevver and KHAN, Akram (2016). The antioxidant activity of some curcuminoids and chalcones. Inflammopharmacology, 24 (2), 81-86.
Khan Antioxidant activity of some curcuminoids and chalcones.pdf - Accepted Version
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The antioxidant properties of the synthetic compound (C1)–(C8), which comprised 7 curcuminoids and a chalcone, were evaluated by two complementary assays, DPPH and β-carotene/linoleic acid. It was found that, in general, the free radical scavenging ability of (C1)–(C8) was concentration-dependent. Compounds (C1) and (C4), which contained (4-OH) phenolic groups, were found to be highly potent antioxidants with higher antioxidant values than BHT suggesting that synthetic curcuminoids are more potent antioxidants than standard antioxidants like BHT. Using β-carotene-linoleic acid assay, only the water-soluble 2, 4,6-trihydroxyphenolic chalcone (C5) showed 85.2 % inhibition of the formation of conjugated dienes reflecting on its potent antioxidant activity.
|Research Institute, Centre or Group:||Biomolecular Sciences Research Centre|
|Depositing User:||Akram Khan|
|Date Deposited:||06 Jun 2016 11:39|
|Last Modified:||07 Dec 2016 19:04|
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