The antioxidant activity of some curcuminoids and chalcones

SÖKMEN, Münevver and KHAN, Akram (2016). The antioxidant activity of some curcuminoids and chalcones. Inflammopharmacology, 24 (2), 81-86.

[img] PDF
Khan Antioxidant activity of some curcuminoids and chalcones.pdf - Accepted Version
Restricted to Repository staff only until 17 May 2017.
Available under License All rights reserved.

Download (429kB)
[img] PDF (Acceptance email)
Khan 12365.pdf
Restricted to Repository staff only

Download (99kB)
Official URL:
Link to published version:: 10.1007/s10787-016-0264-5


The antioxidant properties of the synthetic compound (C1)–(C8), which comprised 7 curcuminoids and a chalcone, were evaluated by two complementary assays, DPPH and β-carotene/linoleic acid. It was found that, in general, the free radical scavenging ability of (C1)–(C8) was concentration-dependent. Compounds (C1) and (C4), which contained (4-OH) phenolic groups, were found to be highly potent antioxidants with higher antioxidant values than BHT suggesting that synthetic curcuminoids are more potent antioxidants than standard antioxidants like BHT. Using β-carotene-linoleic acid assay, only the water-soluble 2, 4,6-trihydroxyphenolic chalcone (C5) showed 85.2 % inhibition of the formation of conjugated dienes reflecting on its potent antioxidant activity.

Item Type: Article
Research Institute, Centre or Group: Biomolecular Sciences Research Centre
Identification Number: 10.1007/s10787-016-0264-5
Depositing User: Akram Khan
Date Deposited: 06 Jun 2016 11:39
Last Modified: 23 Oct 2016 21:26

Actions (login required)

View Item View Item


Downloads per month over past year

View more statistics