The antioxidant activity of some curcuminoids and chalcones

SÖKMEN, Münevver and KHAN, Akram (2016). The antioxidant activity of some curcuminoids and chalcones. Inflammopharmacology, 24 (2), 81-86.

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Official URL: http://link.springer.com/article/10.1007/s10787-01...
Link to published version:: 10.1007/s10787-016-0264-5

Abstract

The antioxidant properties of the synthetic compound (C1)–(C8), which comprised 7 curcuminoids and a chalcone, were evaluated by two complementary assays, DPPH and β-carotene/linoleic acid. It was found that, in general, the free radical scavenging ability of (C1)–(C8) was concentration-dependent. Compounds (C1) and (C4), which contained (4-OH) phenolic groups, were found to be highly potent antioxidants with higher antioxidant values than BHT suggesting that synthetic curcuminoids are more potent antioxidants than standard antioxidants like BHT. Using β-carotene-linoleic acid assay, only the water-soluble 2, 4,6-trihydroxyphenolic chalcone (C5) showed 85.2 % inhibition of the formation of conjugated dienes reflecting on its potent antioxidant activity.

Item Type: Article
Research Institute, Centre or Group: Biomolecular Sciences Research Centre
Identification Number: 10.1007/s10787-016-0264-5
Depositing User: Akram Khan
Date Deposited: 06 Jun 2016 11:39
Last Modified: 07 Dec 2016 19:04
URI: http://shura.shu.ac.uk/id/eprint/12365

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