SOLTANI, H., BRUCE, C. and FRASER, R. B. (1999). Observational study of maternal anthropometry and fetal insulin. Archives of disease in childhood : fetal and neonatal, 81 (2), F122-F124.Full text not available from this repository.
Aims- To examine the relation between maternal body fat and fetal metabolism.Methods- In this observational study, cord blood samples were collected from 60 infants of healthy women for the measurement of insulin and C peptide concentrations. Maternal weight, height, body mass index (BMI) and body composition (skin-fold thickness measurements and bioelectrical impedance) were assessed at 13-15 weeks of gestation. Twenty five of the volunteers agreed to have a 75g oral glucose tolerance test at 28-31 weeks of gestation.Results- Positive correlations were observed with both cord insulin or C peptide concentrations and maternal early pregnancy BMI (r=0.44, p=0.002 and r=0.33, p=0.008, respectively). There was no significant correlation between cord insulin or C peptide concentrations and birthweight or birth weight centiles.Conclusion- Maternal BMI could be a predictor of fetal cord insulin concentration.
|Research Institute, Centre or Group:||Centre for Health and Social Care Research|
|Depositing User:||Sarah Ward|
|Date Deposited:||02 Mar 2010 16:56|
|Last Modified:||02 Mar 2010 17:00|
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