Items where SHU Author is "Le Maitre, Christine"

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Article

PHILLIPS, K.L.E., CULLEN, K., CHIVERTON, N., MICHAEL, A.L.R., COLE, A.A., BREAKWELL, L.M., HADDOCK, G., BUNNING, R.A.D, CROSS, A.K. and LE MAITRE, C.L. (2015). Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes. Osteoarthritis and Cartilage, 23 (7), 1165-1177.

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BINCH, A L A, COLE, A A, BREAKWELL, L M, MICHAEL, A L R, CHIVERTON, N, CREEMERS, L B, CROSS, Alison and LE MAITRE, Christine (2015). Class 3 semaphorins expression and association with innervation and angiogenesis within the degenerate human intervertebral disc. Oncotarget. (In Press)

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THORPE, A A, SAMMON, Chris and LE MAITRE, Christine (2015). 'Cell or Not to Cell' that is the question : for intervertebral disc regeneration? Journal of Stem Cells Research, Development and Therapy, 2 (1).

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JOHNSON, Zariel I, GOGATE, Shilpa S, DAY, Rebecca, BINCH, Abbie, MARKOVA, Dessislava Z, CHIVERTON, Neil, COLE, Ashley, CONNER, Matthew, SHAPIRO, Irving M, LE MAITRE, Christine and RISBUD, Makarand V (2015). Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: novel HIF-1-mediated regulation of aquaporins in NP cells. Oncotarget, 6 (14), 11945-11958.

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ZAINI, R, HAYWOOD-SMALL, S, CROSS, Neil and LE MAITRE, Christine (2015). Differential interactions of Falcarinol combined with anti-tumour agents on cellular proliferation and apoptosis in human lymphoid leukaemia cell lines. Journal of Blood Disorders and Transfusion, 6 (2).

BINCH, A L, LE MAITRE, Christine, THORPE, A A and HUGHES, S P (2015). Degeneration of the intervertebral disc with new approaches for treating low back pain. Journal of neurosurgical sciences, 59 (1), 47-61.

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BINCH, Abbie L.A., COLE, Ashley A., BREAKWELL, Lee M, MICHAEL, Anthony, CHIVERTON, Neil, CROSS, Alison K. and LE MAITRE, Christine L. (2014). Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degeneration. Arthritis research & therapy, 16 (5), p. 416.

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MADER, Kerstin T, LE MAITRE, Christine L and SAMMON, Chris (2014). Characterisation of intervertebral discs using MID-IR spectroscopic imaging. Global Spine Journal, 4, p. 58.

DUNN, S.L., WILKINSON, J.M., CRAWFORD, A., LE MAITRE, Christine and BUNNING, R.A.D. (2014). Cannabinoid WIN-55,212-2 mesylate inhibits interleukin-1β induced matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase expression in human chondrocytes. Osteoarthritis and Cartilage, 22 (1), 133-144.

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MAHBUB, Amani A, LE MAITRE, Christine, HAYWOOD-SMALL, Sarah, MCDOUGALL, Gordon J, CROSS, Neil and JORDAN-MAHY, N. (2013). Differential effects of polyphenols on proliferation and apoptosis in human myeloid and lymphoid leukemia cell lines. Anti-cancer agents in medicinal chemistry, 13 (10), 1601-1613.

PHILLIPS, Kate L.E., CHIVERTON, Neil, MICHAEL, Anthony L.R., COLE, Ashley A, BREAKWELL, Lee M, HADDOCK, Gail, BUNNING, Rowena A.D., CROSS, Alison K. and LE MAITRE, Christine L. (2013). The cytokine and chemokine expression profile of nucleus pulposus cells: implications for degeneration and regeneration of the intervertebral disc. Arthritis research & therapy, 15 (6), R213.

LAMA, P., LE MAITRE, Christine, DOLAN, P., TARLTON, J. F., HARDING, I. J. and ADAMS, M. A. (2013). Do intervertebral discs degenerate before they herniate, or after? The Bone & Joint Journal, 95-B (8), 1127-1133.

PHILLIPS, Kate Louise Eve, JORDAN-MAHY, Nikki, NICKLIN, Martin J. H. and LE MAITRE, Christine Lyn (2013). Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degeneration. Annals of the Rheumatic Diseases, 72, 1860-1867.

DAHLAWI, Haytham, JORDAN-MAHY, Nicola, CLENCH, Malcolm, MCDOUGALL, Gordon J. and LE MAITRE, Christine Lyn (2013). Polyphenols are responsible for the proapoptotic properties of pomegranate juice on leukemia cell lines. Food Science and Nutrition, 1 (2), 196-208.

WANG, Jianru, TIAN, Ye, PHILLIPS, Kate L. E., CHIVERTON, Neil, HADDOCK, Gail, BUNNING, Rowena, CROSS, Alison, SHAPIRO, Irving M., LE MAITRE, Christine and RISBUD, Makarand V. (2013). Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1. Arthritis & rheumatism, 65 (3), 832-842.

WANG, Jianru, TIAN, Ye, PHILLIPS, Kate L. E., CHIVERTON, Neil, HADDOCK, Gail, BUNNING, Rowena, CROSS, Alison, SHAPIRO, Irving M., LE MAITRE, Christine and RISBUD, Makarand V. (2013). Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1. Arthritis & rheumatism, 65 (3), 832-842.

ZAINI, Rana G., BRANDT, Kirsten, CLENCH, Malcolm and LE MAITRE, Christine (2012). Effects of bioactive compounds from carrots (Daucus carota L.), polyacetylenes, beta-carotene and lutein on human lymphoid leukaemia cells. Anti-Cancer Agents in Medicinal Chemistry, 12 (6), 640-652.

DUNN, S.L., WILKINSON, J. M., CRAWFORD, A., LE MAITRE, C. and BUNNING, R. A. D. (2012). Cannabinoids: novel therapies for arthritis? Future Medicinal Chemistry, 4 (6), 713-725.

DAHLAWI, H, JORDAN-MAHY, Nikki, CLENCH, Malcolm and LE MAITRE, Christine (2012). Bioactive actions of pomegranate fruit extracts on leukemia cell lines In vitro hold promise for new therapeutic agents for leukemia. Nutrition and Cancer, 64 (1), 100-110.

ZAINI, R, CLENCH, Malcolm and LE MAITRE, Christine (2011). Bioactive chemicals from carrot (Daucus carota) juice extracts for the treatment of leukemia. Journal of Medicinal Food, 14 (11), 1-10.

LE MAITRE, C. L., FRAIN, J., MILLWARD-SADLER, J., FOTHERINGHAM, A. P., FREEMONT, A. J. and HOYLAND, J. A. (2009). Altered integrin mechanotransduction in human nucleus pulposus cells derived from degenerated discs. Arthritis & rheumatism, 60 (2), 460-469.

LE MAITRE, C. L., FOTHERINGHAM, A. P., FREEMONT, A. J. and HOYLAND, J. A. (2009). Development of an in vitro model to test the efficacy of novel therapies for IVD degeneration. Journal of tissue engineering and regenerative medicine, 3 (6), 461-469.

LE MAITRE, C. L., FREEMONT, A. J. and HOYLAND, J. A. (2009). Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells. Arthritis research & therapy, 11 (5), R137.

POCKERT, A. J., RICHARDSON, S. M., LE MAITRE, C. L., LYON, M., DEAKIN, J. A., FREEMONT, A. J. and HOYLAND, J. A. (2009). Modified expression of the ADAMTS enzymes and tissue inhibitor of metalloproteinases 3 during human intervertebral disc degeneration. Arthritis & rheumatism, 60 (2), 482-491.

LE MAITRE, C. L., BAIRD, P., FREEMONT, A. J. and HOYLAND, J. A. (2009). An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue. Arthritis research & therapy, 11 (1), R20.

HEATHFIELD, S. K., LE MAITRE, C. L. and HOYLAND, J. A. (2008). Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration. Arthritis research & therapy, 10 (4), R87.

ALI, R., LE MAITRE, C., RICHARDSON, S., HOYLAND, J. and FREEMONT, A. (2008). Connective tissue growth factor expression in human intervertebral disc: implications for angiogenesis in intervertebral disc degeneration. Biotechnic & Histochemistry, 83 (5), 239-245.

LE MAITRE, C. L., FRAIN, J., FOTHERINGHAM, A. P., FREEMONT, A. J. and HOYLAND, J. A. (2008). Human cells derived from degenerate intervertebral discs respond differently to those derived from non-degenerate intervertebral discs following application of dynamic hydrostatic pressure. Biorheology, 45 (5), 563-575.

HOYLAND, J. A., LE MAITRE, C. and FREEMONT, A. J. (2008). Investigation of the role of IL-1 and TNF in matrix degradation in the intervertebral disc. Rheumatology, 47 (6), 809-814.

LALLY, Sarah, MACKENZIE, Paul, LEMAITRE, Christine L, FREEMONT, Tony J and SAUNDERS, Brian R (2007). Microgel particles containing methacrylic acid: pH-triggered swelling behaviour and potential for biomaterial application. Journal of colloid and interface science, 316 (2), 367-375.

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LE MAITRE, Christine Lyn, HOYLAND, Judith Alison and FREEMONT, Anthony J (2007). Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1β and TNFα expression profile. Arthritis research & therapy, 9 (4), R77.

LE MAITRE, C L, POCKERT, A, BUTTLE, D J, FREEMONT, A J and HOYLAND, J A (2007). Matrix synthesis and degradation in human intervertebral disc degeneration. Biochemical Society transactions, 35 (Pt 4), 652-655.

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LE MAITRE, Christine Lyn, FREEMONT, Anthony John and HOYLAND, Judith Alison (2007). Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration. Arthritis research & therapy, 9 (3), R45.

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LE MAITRE, Christine, HOYLAND, Judith A and FREEMONT, Anthony J (2007). Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc: an in situ zymographic and gene therapy study. Arthritis research & therapy, 9 (4), R83.

SAUNDERS, Jennifer M., TONG, Tony, LE MAITRE, Christine, FREEMONT, Tony J. and SAUNDERS, Brian R. (2007). A study of pH-responsive microgel dispersions: from fluid-to-gel transitions to mechanical property restoration for load-bearing tissue. Soft Matter, 3 (4), 486-494.

LE MAITRE, C L, FREEMONT, A J and HOYLAND, J A (2006). Human disc degeneration is associated with increased MMP 7 expression. Biotechnic & Histochemistry, 81 (4-6), 125-131.

LE MAITRE, Christine L, FREEMONT, Anthony J and HOYLAND, Judith A (2006). A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration. International Journal Of Experimental Pathology, 87 (1), 17-28.

LE MAITRE, Christine L, RICHARDSON, Stephen M A, BAIRD, Pauline, FREEMONT, Anthony J and HOYLAND, Judith A (2005). Expression of receptors for putative anabolic growth factors in human intervertebral disc: implications for repair and regeneration of the disc. The Journal of Pathology, 207 (4), 445-452.

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LE MAITRE, Christine Lyn, FREEMONT, Anthony J and HOYLAND, Judith Alison (2005). The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration. Arthritis Research & Therapy, 7 (4), R732-R745.

LE MAITRE, Christine Lyn, FREEMONT, Anthony J and HOYLAND, Judith Alison (2004). Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc. The Journal of Pathology, 204 (1), 47-54.

LE MAITRE, Christine Lyn, HOYLAND, Judith Alison and FREEMONT, Anthony J (2004). Studies of human intervertebral disc cell function in a constrained in vitro tissue culture system. Spine, 29 (11), 1187-1195.

FREEMONT, A J, WATKINS, A, LE MAITRE, C, BAIRD, P, JEZIORSKA, M, KNIGHT, M T N, ROSS, E R S, O'BRIEN, J P and HOYLAND, J A (2002). Nerve growth factor expression and innervation of the painful intervertebral disc. The Journal of Pathology, 197 (3), 286-292.

FREEMONT, A J, WATKINS, A, LE MAITRE, Christine, JEZIORSKA, M and HOYLAND, J A (2002). Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy. The Journal of Pathology, 196 (4), 374-379.

LE MAITRE, C L, BYERS, R J, LIU YIN, J A, HOYLAND, J A and FREEMONT, A J (2001). Dual colour FISH in paraffin wax embedded bone trephines for identification of numerical and structural chromosomal abnormalities in acute myeloid leukaemia and myelodysplasia. Journal of clinical pathology, 54 (9), 730-733.

FREEMONT, Tony J, LE MAITRE, Christine, WATKINS, Alex and HOYLAND, Judith A (2001). Degeneration of intervertebral discs: current understanding of cellular and molecular events, and implications for novel therapies. Expert reviews in molecular medicine, 3 (11), 1-10.

This list was generated on Tue Sep 1 12:10:01 2015 UTC.