Emerging applications in mass spectrometry imaging; enablers and roadblocks

RUSSO, C., HEATON, C., FLINT, L., VOLOACA, Oana, HAYWOOD-SMALL, Sarah, CLENCH, Malcolm, FRANCESE, Simona and COLE, Laura (2020). Emerging applications in mass spectrometry imaging; enablers and roadblocks. Journal of Spectral Imaging, 9, 1-21.

Preview

PDF Voloaca-EmergingApplicationsMass(VoR).pdf - Published Version Creative Commons Attribution. Download (1MB) | Preview

Abstract

© 2020 The Authors. Mass spectrometry imaging (MSI) is a powerful and versatile technique able to investigate the spatial distribution of multiple non-labelled endogenous and exogenous analytes simultaneously, within a wide range of samples. Over the last two decades, MSI has found widespread application for an extensive range of disciplines including pre-clinical drug discovery, clinical applications and human identification for forensic purposes. Technical advances in both instrumentation and software capabilities have led to a continual increase in the interest in MSI; however, there are still some limitations. In this review, we discuss the emerging applications in MSI that significantly impact three key areas of mass spectrometry (MS) research—clinical, pre-clinical and forensics—and roadblocks to the expansion of use of MSI in these areas.

Item Type:	Article
Identification Number:	https://doi.org/10.1255/jsi.2020.a13
Page Range:	1-21
SWORD Depositor:	Symplectic Elements
Depositing User:	Symplectic Elements
Date Deposited:	25 Nov 2020 15:45
Last Modified:	17 Mar 2021 20:00
URI:	https://shura.shu.ac.uk/id/eprint/27669

Actions (login required)

View Item

Downloads

Publication Metrics