Cancer-Related Genetic Testing and Personalized Medicine for Adolescents: A narrative review of impact and understanding

VETSCH, Janine, WAKEFIELD, Claire E, WARBY, Meera, TUCKER, Katherine, PATTERSON, Pandora, MCGILL, Brittany C, METCALFE, Alison, COHN, Richard J and FARDELL, Joanna E (2018). Cancer-Related Genetic Testing and Personalized Medicine for Adolescents: A narrative review of impact and understanding. Journal of Adolescent and Young Adult Oncology, 7 (3).

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Abstract

Genetic testing is becoming increasingly available for adolescents who are undergoing cancer treatment or at risk of cancer predisposition syndromes. With this narrative review, we aimed to synthesize the evidence on psychosocial outcomes and adolescents' understanding of genetic testing-thus far, an underresearched topic. Both psychological benefits and harms of predictive testing were reported in adolescents from high-risk families. Harms were mainly related to cancer-specific distress and increased worries. Findings on genetic understanding were sparse. Future studies should focus on psychosocial outcomes and adolescents' understanding undergoing genetic testing and enabling access to genetic counseling pre-testing and post-testing.

Item Type:	Article
Research Institute, Centre or Group - Does NOT include content added after October 2018:	Centre for Health and Social Care Research
Identification Number:	https://doi.org/10.1089/jayao.2017.0102
Depositing User:	Justine Gavin
Date Deposited:	23 Jul 2018 13:25
Last Modified:	18 Mar 2021 10:45
URI:	https://shura.shu.ac.uk/id/eprint/21992

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